She is widely in demand as a soloist and chamber musician and has appeared with the Moscow Virtuosi and Vladimir Spivakov, the Buffalo Philharmonic, the St. Luke's Chamber Ensemble, the Columbus Symphony Orchestra, the Chamber Orchestra of Philadelphia, and many others. Ms. Polonsky has also collaborated with the Guarneri, Orion, and Audubon Quartets, and with such musicians as Mitsuko Uchida, David Shifrin, Richard Goode, Ida and Ani Kavafian, Cho-Liang Lin, Arnold Steinhardt, Anton Kuerti, Gary Hoffman, and Fred Sherry. She is regularly invited to perform chamber music at festivals such as Marlboro, Chamber Music Northwest, Seattle, Moab, Santa Fe, Bridgehampton, Bard, and Caramoor, as well as a frequent guest at the Chamber Music Society of Lincoln Center.

Anna Polonsky made her solo piano debut at the age of seven at the Special Central Music School in Moscow, Russia. She emigrated to the United States in 1990, and attended high school at the Interlochen Arts Academy in Michigan. She received her Bachelor of Music diploma from The Curtis Institute of Music, where she worked with the renowned pianist Peter Serkin, and continued her studies with Jerome Lowenthal, earning her Master's Degree from the Juilliard School. A Steinway Artist, Polonsky was a recipient of a Borletti-Buitoni Trust Fellowship in 2003. In addition to performing, she serves on the piano faculty of VassarCollege.